Distribution of Associated Anomalies in Cleft Lip and Palate in Pakistani Population

Abstract

Objective: A cross-sectional study design was used to estimate frequency of non-identical anomalies with cleft lip and palate (CLP). Prevalence of disease in Pakistani population. Analysis with similar disorders. Methodology: A cross-sectional study design was used to estimate frequency of non-identical anomalies with cleft lip and palate (CLP). The duration of study was from January 2022 to January 2023. The sample size was 100. Data was analyzed by using SPSS version 16. A p-value less than 00.5 were considered significant. Results: In this study a total of 100 patients were recruited from different hospitals of Lahore. All of them were examined physically and classified in different categories including Cleft Palate Only, Cleft Lip and Palate. Out of these 100 patients 55(55%) were males and 45(45%) were females. 11 (11%) of them were having Cleft Lip only, 18(18%) Cleft Palate only, and 71(71%) having Cleft Lip and Palate. Conclusion: The prevalence of the associated anomalies is high in those patients who have family history of cleft lip and palate. In this study we get to know that the males (55%) are more affected than females (45%). There is a very high prevalence of tooth agenesis in cleft patients as compared to other anomalies. Complete cleft lip and palate is more present in males as compared to females. Consanguinity is the major reason for this disorder. In this study we also get to know that in our data there is high prevalence of cousin marriages in Pakistani population. 

Keywords:  CLP, Prevalence, Orofacial Clefting, Tooth Agenesis.