Cognitive Functioning and Seizure: Their Effects on the Quality Life of Patients with Epilepsy

Abstract

Objectives: The aim of this study is to explore the connection between cognitive abilities and quality of life among individuals with epilepsy, as well as the impact that cognitive impairments may have on various aspects of daily living. 

Methods: A total of 400 individuals, comprising both epilepsy patients and healthy controls, underwent evaluations using standardized measures to assess cognitive abilities and quality of life. The domains analyzed included memory, attention, executive function, emotional well-being, and the effects of seizures. Data were collected via hospital visits and community outreach. Back-translation techniques were employed in the pilot study to guarantee the linguistic accuracy of the assessment tools. 

Results: Epilepsy patients exhibited significantly poorer cognitive performance across several subdomains when compared to healthy participants. Additionally, quality of life scores were substantially reduced in dimensions such as mood, energy, daily activities, and stress related to seizures. A strong positive correlation was identified between cognitive functioning and overall quality of life. Regression analysis indicated that the severity of seizures and quality of life domains were significant predictors of cognitive performance in patients with epilepsy. 

Conclusion: Individuals with epilepsy demonstrate significant deficits in cognitive functioning and diminished quality of life. These cognitive difficulties are closely associated with seizure severity and psychosocial challenges, underscoring the importance of integrated treatment strategies that focus on both neurological and quality of life considerations.