Comparison Of Effectiveness Of Prp (Platelet Rich Plasma) Versus Conventional Wound Care In Gape Wound Healing After Caesarean Sections

Abstract

Background: Wound healing complications, such as superficial wound dehiscence, are common following Caesarean sections and contribute to increased morbidity and prolonged hospital stays. Platelet-rich plasma (PRP), rich in growth factors, has emerged as a potential adjunct to enhance tissue regeneration and wound healing. Objective This current research aims to compare the outcomes of autologous PRP (platelet-rich plasma) injection versus conventional wound care in gape wound healing in terms of mean reduction in REEDA score. Methods: This randomized controlled trial was conducted at the Department of Obstetrics and Gynecology, Sir Ganga Ram Hospital, Lahore. A total of 60 patients with superficial wound dehiscence post-Caesarean section were randomized into Group A (PRP, n=30) and Group B (conventional wound care, n=30). Wound healing was assessed using the REEDA scale on Days 1, 3, 5, 7, and 10. Results: The PRP group demonstrated significantly faster wound healing with lower REEDA scores by Day 10 (1.4 ± 0.8 vs. 3.2 ± 1.1; p<0.001). The PRP group showed significantly faster wound healing than the conventional care group, as reflected by lower REEDA scores from Day 3 onwards. On Day 1, the REEDA scores were comparable (11.3 ± 1.2 vs. 11.5 ± 1.4; p=0.58), but by Day 10, the PRP group had a much lower mean score (1.4 ± 0.8) compared to the conventional group (3.2 ± 1.1; p<0.001). Infection was less common in the PRP group, occurring in only 6.6% of patients compared to 13.3% in the conventional care group (p=0.045). Patient satisfaction was significantly higher among PRP recipients (p=0.004). Conclusion: It is concluded that PRP is superior to conventional wound care in promoting faster and better-quality wound healing after Caesarean section wound dehiscence. PRP application leads to improved healing outcomes, reduced infection rates, decreased pain, shorter hospitalization, and higher patient satisfaction.

Keywords: PRP, WHO, C-section, Wound, Effectiveness, Hospital